MegaMucosa is the first complete mucosal support supplement of its kind, formulated to REBUILD a healthy mucosal barrier. MegaMucosa also contains dairy-free immunoglobulins clinically shown to support a healthy immune response in the mucosa and a state-of-the-art flavobiotic clinically shown to support microbial diversity and alleviate barrier dysfunction, otherwise known as leaky gut.
MegaMucosa™ contains the following ingredients:
ImmunoLin® – A proprietary, dairy-free immunoglobulin concentrate that has been extensively studied clinically to help neutralise LPS and other toxins in the intestinal lumen before they reach the intestinal lining. This prevents not just intestinal, but systemic intoxication and inflammation. It provides robust intestinal repair support, increases immune cells in the gut mucosa, and has been shown to be great for IBS/IBD and diarrhoea.
Proprietary Amino Acid Blend – Four key amino acids (L-Proline, L-Serine. L-Threonine, L-Cysteine) have been studied to increase colonic mucin production by a whopping 95% without affecting protein turnover. By building a thicker and healthier mucosal barrier, they protect the gut mucosa even in inflammatory situations, help recalibrate the gut microbiota and promote the regrowth of bacteria populations, and ensure mucosal healing can take place.* L-Glutamine is not used because relatively high doses are needed as its mechanism is energy provision for intestinal epithelial cells versus direct mucin production. At high doses, it affects protein turnover, which can then cause other issues such as glutamate excess, mTOR activation and more.
MicrobiomeX® – A state-of-the-art Flavobiotic™ clinically shown to reduce intestinal inflammation by inhibiting NF-kB, blocking JNK-stress activated pathways, protecting against experiemental colitis and reduce risk of IBD. In 12 weeks, it
increased butyrate production by 21%, reduced fecal calprotectin levels by 22% (consequent reduction in pathogen load), and increased the commensal Clostridium cluster XIVa by 44%. By improving production of antioxidants such as glutathione in the intestinal cells, it also protects against oxidative damage in the gut.
*Higashiguchi T, Hasselgren PO, Wagner K, Fischer JE. Effect of glutamine on protein synthesis in isolated intestinal epithelial cells. JPEN J Parenter Enteral Nutr. 1993 Jul-Aug;17(4):307-14. doi: 10.1177/0148607193017004307. PMID: 8271353.